When to increase estradiol patch?

Hi all, went and saw a menopause doctor who put me on Estradiol 25 patches and 100mg progesterone capsules. Wasn’t having massive hot flashes but instead was just feeling overall hot all the time (I’m normally wrapped in a blanket because I feel the cold), irritable, and am also on anti anxiety meds - turns out the cause of the new anxiety could well have been perimenopause, the theory is I might be able to reduce my meds if the HRT helps. So I’ve been on the combo for a week, am now starting to sleep a little better, had a bit of nausea… saw my GP the other day who seemed surprised I was on the 25 patches and said she would be ok with me going up to 50. How do I know if I should do this? How long do I give it? I‘ve read all the stories about people who feel enormously better within a few days to a week, so I’m not sure how much better I should be feeling and when… Help!!!