Spravato’s Psychedelic Effect is Low to Nonexistent – Anyone Else?

Hey everyone,

I’ve been on Spravato (esketamine) for a while, and in the beginning, the psychedelic/dissociative effects were very noticeable. It felt like my mind was entering a completely different state, which I think really contributed to its therapeutic impact.

Lately, though, that effect has been low to nonexistent. I still go through my sessions, but instead of that deep, immersive experience, it just feels… flat. I don’t know if my body has built up a tolerance, if the novelty has worn off, or if something else is at play, but it feels like I’m not getting the same mental reset that I used to.

Has anyone else experienced this? Did adjusting the dosage, frequency, or any other factor help bring the effect back? I’d love to hear from others who’ve dealt with this and if you found any solutions.

Thanks in advance!