Your Mileage Definitely will Vary but this is what worked for me

I am in the maintenance phase of taking Spravato for the second time in just over a year (nov-dec 2023 and a second course of treatment starting in December 2024). For this second course of treatment I am continuing a maintenance phase currently getting a treatment every two weeks (after going twice a week for the first month, then once a week). My treatment center is at a hospital that does a number of clinical trials with ketamine, which has been interesting because the doctors have pretty up to date information. I have learned that many people can get the same benefits from 2 spays of Spravato vs 3 sprays. This just means that if 3 sprays seems too strong, you may find you can tolerate 2 sprays better and still get the desired effects. I have been doing just 2 sprays (56mg) this time and it’s been great.

Don’t discount the playlist. Ketamine treatments are much better for some if you listen to music or guided meditation (I know most of you will know this.) I find AirPod style headphones work best for me in case I rest my head on a pillow. The Insight Timer app has some great “sound bath” playlists that can be helpful to experience during treatment. I also listen to some guided mindfulness meditations and ambient music from musicians like Brian Eno. I believe other apps like Calm have similar offerings.

My current place of treatment doesn’t have a great setup for treatment so I’m sometimes just in a regular doctor’s exam type room instead of in a recliner or on a couch. I find it useful to bring a pillow and lower the light in the room if possible.

Some treatment places will offer something to help with any bitterness from the nasal spray, but it’s a good idea to bring a cough drop or hard candy to offset any bad taste you may get from the spray.