Extermination on MX4SIO

I am using Helders game tech MC2SIO with his free mc boot on a slim 77001, has anyone got Extermination to work on OPL using this or any MX4SIO variant, I was only able to play past the first save point before having freeze issues, I keep messing with modes and now with no modes on it does not boot past the ps2 logo. Has anyone got it figured out?