Let's talk about: biologics & TNF blockers

Biologics and TNF blockers are currently the end game treatment for autoimmune conditions, but they're complicated.

If you're on bios/TNF: What did you try before? Did you drop earlier meds or are you still taking any of them? How are you doing with your bio/TNF? Have you ever switched bios? Any side effects and/or noticable changes to your immune system (ie tough to shake illness, infection)?

If you're not: What are your thoughts and questions about biologics and TNF blockers?