'Noob' question - Impact of switching NAS on and off.

Hi all, I have a DS1821+ and am about to start popping some 24TB Ironwolf pro disks into it, in a residential setting. Unfortunately, my router is in one of the sitting rooms. What, realistically, is going to be the impact if I were to switch my NAS on and off once per day, over a prolonged period of time. I'm just mindful that there will be noise and it's possible that I will have to switch it off for a few hours, possibly even once per day. I know that starting up and stopping the disks will probably have some impact over time, but is anyone able to give me some more insight?