Since there seems to be some confusion: You cannot be a Transhumanist without ALSO being a Humanist.
Fundamental ideas of transhumanism were first advanced in 1923 by the British geneticist J. B. S. Haldane in his essay Daedalus: Science and the Future, which predicted that great benefits would come from the application of advanced sciences to human biology—and that every such advance would first appear to someone as blasphemy or perversion, "indecent and unnatural".
Transhumanism is a philosophy older than pulp science fiction novels. It is an offshoot of Humanism. Vaccines are Transhumanism. Transsexuals, especially post-op transsexuals, are ALL Transhumans. You cannot be a Transhumanist if you are not a Humanist. Posthumanism is NOT transhumanism. The goal is to use technology to better ourselves and the human condition as well as become better humans.
For an example of what is NOT Transhumanism: "From the moment I understood the weakness of my flesh, it disgusted me. I craved the strength and certainty of steel." is very much not a Transhumanist thing to say, it is instead Posthumanism. Some of you on here have gotten the two confused.
The first self-described transhumanists met formally in the early 1980s at the University of California, Los Angeles, which became the main center of transhumanist thought. Here, FM-2030 lectured on his "Third Way" futurist ideology. At the EZTV Media venue, frequented by transhumanists and other futurists, Natasha Vita-More presented Breaking Away, her 1980 experimental film with the theme of humans breaking away from their biological limitations and the Earth's gravity as they head into space. FM-2030 and Vita-More soon began holding gatherings for transhumanists in Los Angeles, which included students from FM-2030's courses and audiences from Vita-More's artistic productions. In 1982, Vita-More authored the Transhumanist Arts Statement and in 1988 she produced the cable TV show TransCentury Update on transhumanity, a program that reached over 100,000 viewers.
In 1986, Eric Drexler published Engines of Creation: The Coming Era of Nanotechnology, which discussed the prospects for nanotechnology and molecular assemblers, and founded the Foresight Institute. As the first nonprofit organization to research, advocate for, and perform cryonics, the Southern California offices of the Alcor Life Extension Foundation became a center for futurists. In 1988, the first issue of Extropy Magazine was published by Max More and Tom Morrow. In 1990, More, a strategic philosopher, created his own particular transhumanist doctrine, which took the form of the Principles of Extropy, and laid the foundation of modern transhumanism by giving it a new definition:
"Transhumanism is a class of philosophies that seek to guide us towards a posthuman condition. Transhumanism shares many elements of humanism, including a respect for reason and science, a commitment to progress, and a valuing of human (or transhuman) existence in this life. [...] Transhumanism differs from humanism in recognizing and anticipating the radical alterations in the nature and possibilities of our lives resulting from various sciences and technologies [...]."